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  • Celiac Disease
    Also known as celiac sprue or gluten sensitive enteropathy. This is a digestive and autoimmune disorder that causes damage to the lining of the small intestine when foods with gluten are eaten. About 1 in 100 people suffer from this condition.  
Submitted by PatientsEngage on 24 November 2015
Celiac Disease Overview

What is celiac disease?

Celiac or Coeliac Disease is also known as celiac sprue or gluten sensitive enteropathy. This is a digestive and inherited autoimmune disorder that causes damage to the lining of the small intestine (villi) when foods with gluten are eaten. Villi are finger like projections that protrude from the lining of small intestine. They help in digestive process by maximizing the nutrient absorption. 
 

Image 1: Normal villi and villous atrophy in celiac disease

Gluten is a form of protein found in some grains like rye, barley, wheat etc. Intake of gluten containing foods causes damage to the intestine and makes it hard for the body to absorb nutrients like fat, calcium, iron and folate. It can affect children and adults, and becomes more common in older people. To read more, click on https://www.patientsengage.com/healthy-living/gluten-facts-myths.

Apart from genetics, the suspected causes include gastrointestinal infections, intestinal microbes, or early initiation of gluten in an individual. People with other autoimmune conditions and chromosomal disorders are more likely to have this. Damage to small intestines and impaired nutrient absorption leads to malnutrition. In children it can cause stunting. Diagnosis is difficult at initial stages as people don’t show symptoms.There is no cure for this disease. Following a strict gluten-free diet and regular follow up with health care provider is necessary.

Condition

Stories

  • Diet Changes That Helped Them Manage Chronic Conditions
    Diet changes are an integral part of management of many chronic conditions. Here are real life experiences of eight women who incorporated diet and nutrition changes in their disease management regimen.  Celiac Disease When Jeeva Anna George was diagnosed with Celiac disease, an uncommon digestive disorder causing inflammation of the small intestine, her whole life began revolving around food. Here she talks at length about her personal journey and how she learnt the hard way to control…
  • A person in a blue shirt with head cut off holding hand up to say no to a loaf of bread
    Gluten Facts And Myths
    Is going gluten-free just a fad or is there a valid reason to consider this lifestyle change? Dr. Shital Raval explains what is gluten and the difference between wheat allergy, gluten intolerance and celiac disease. Remember to bookmark this. Along with the growing trend of multigrain goods in the food market and nutritional world, there has also been a proliferating market for gluten-free food products. This has been hand-in-hand with emergent reports of gluten sensitivities and intolerance…
  • When Going Gluten Free Is a Necessity
    When Jeeva Anna George was diagnosed with Celiac disease, an uncommon digestive disorder causing inflammation of the small intestine, her whole life began revolving around food. Here she talks at length about her personal journey and how she learnt the hard way to control the disease by strictly following a gluten free diet. At what age did you discover you had celiac disease? My symptoms started when I was 25 but I was diagnosed a month after turning 27. What were your initial symptoms? My…
  • Overview of Digestive Disorders and Gastrointestinal Diseases
    Endoscopy guru and leading gastroenterologist Dr Vipulroy Rathod’s comprehensive interview on gastrointestinal diseases and cancers makes for an enlightening and interesting read. What is Gastroenterology? Gastroenterology is the branch of medicine focused on the digestive system and its disorders. Diseases affecting the gastrointestinal tract, which include the organs from mouth to anus, along the alimentary canal, are the focus of this specialty. Physicians practicing in this field are called…
  • Is Gluten Always the Culprit?
    Or is it sometimes the fall guy for other allergens? Dietitian Ujjwala Baxi tells you what to do if you think you are gluten-sensitive. First tip: Do not rush into a gluten-free diet plan. I first heard about gluten sensitivity during my college days when I was studying nutrition. During my year of internship in a 1,000-bed government hospital in India, I heard of only 3 gluten sensitive cases that were referred to the dietary department for a specific meal plan. This was 10 years back. Now, in…
  • Celiac Disease Management
    Management of Celiac Disease
    Principles of a lifestyle free of gluten will entail: Avoid all foods made from wheat, rye and barley. Examples – daliya, wheat roti, paratha, noodles, pasta, naan, kulcha, poori, breads, biscuits, buns, patties, cookies, all sooji, vermicelli and maida items. Be aware of hidden sources of gluten and make your choice.  Condiments such as soy sauce, salad dressing, cheese spreads, bottled smoothies and milk shakes, malt vinegar also contain gluten. Processed foods are most likely to…
  • Celiac Disease Treatment
    Celiac Disease Treatment
    There is no cure for celiac disease. The only treatment is gluten-free diet which does not contain wheat, rye, barley and their derivatives. Gluten is found in biscuits, bakery items, saucesbread, pasta, breakfast cereals, snacks and other processed foods. Don’t forget to read food labels and see for gluten free alternatives. The disease severity will be varying depending on the patient’s immune response. Some patients can ingest small amounts of gluten without developing symptoms, while others…
  • Celiac Disease Prevention
    Prevention of Celiac Disease
    Can Celiac Disease be prevented? Celiac disease cannot be prevented. But if you have celiac disease, you can prevent the flare-up of symptoms and continual damage to your small intestine by adhering to a strict gluten-free life. For a gluten free diet, read more in Celiac Disease Management section. References: https://www.schaer.com/en-int/faqs/types-of-coeliac-disease https://nationalceliac.org/resources/what-is-celiac-disease-2/?gad_sour… https://www.worldgastroenterology.org/guidelines/…
  • Celiac Disease Types and Stages
    Stages of Celiac Disease and Complications
    Doctors often use Modified Marsh classification based on histopathology to understand various levels of intestinal damage identified in biopsy. Stage 0 – Pre infiltrative mucosa considered as normal. Stage 1 – Increase in the number of intraepithelial lymphocytes (IELS) to more than 25 per 100 electrolytes with a normal crypt/villi ratio. Stage 2 – In addition to the increased IELS, there is an increase in crypt depth without a reduction in villus height. This is known as crypt hyperplasia.…
  • Celiac Disease Diagnosis and Tests
    Celiac Disease Diagnosis and Tests
    Consultation of gastroenterologist and dietitian is important for diagnosing and managing this disease. In order to diagnose the condition, the doctor may suggest some of the following: Physical examination and review of medical history. Blood tests– To measure levels of antibodies and to detect nutritional deficiencies (iron levels). Antibodies such as immunoglobulin A (IgA) anti tissue transglutaminase (tTG) antibodies, IgA anti endomysial antibodies (EMA) and IgA anti deamidated gliadin…