Conditions

The various treatment approaches used for Hemophilia are: Replacement therapy – Missing clotting factors are replaced in the blood. Blood factor concentrates made from donated blood or Recombinant clotting factor (Lab made) are given via IV infusion. This therapy is used in severe Hemophilia cases to prevent bleeding episodes. Emicizumab (monoclonal antibody) is a drug approved for pediatric and adult patients. It helps in preventing bleeding episodes.  Desmopressin – This hormone can…

Below mentioned tests are conducted for diagnosis of Hemophilia: Complete Blood Count (CBC) – It measures the amount of hemoglobin, and the size and number of red blood cells, white blood cells and platelets. Bleeding time test – It is used to access the time for a small incision to stop bleeding. 2 to 9 minute is the normal bleeding time. Activated Partial Thromboplastin Time (aPTT) – It measures the time for blood to clot. 25 to 35 second is the normal time. Clotting factor test – It is used…

Hemophilia is classified based on the deficiency of different clotting factors: Hemophilia A (Classic Hemophilia) – It is the most common type of condition. It occurs due to deficiency of clotting factors VIII. Hemophilia B (Christmas Disease) – It occurs due to deficiency of clotting factor IX. Hemophilia C – It occurs due to deficiency of clotting factors XI. Para hemophilia – It occurs due to clotting factor V deficiency. Based on the percentage of clotting factors and severity, Hemophilia…

Symptoms of Hemophilia depend on the severity of the condition. Early detection is very important, as internal bleeding can be dangerous. Symptoms and signs of hemophilia include: Prolonged bleeding – Excessive bleeding can occur after injuries, surgeries, or dental procedures. It happens because of the absence of clotting factors required to stop bleeding. Fatigue and weakness – Chronic bleeding can lead to anemia, resulting in fatigue and weakness. Easy bruising – Large bruises can be…

Causes and Risk Factors of Hemophilia Hemophilia is often passed down from parents to children through the X chromosome. Mutations in either of the gene for the factor VIII protein or the gene for the factor IX protein leads to the low production of these clotting factors. This change in a copy of the gene that makes factor VIII or factor IX is called a Hemophilia allele. Both of these factors are found on the X chromosome.                  …

What is Hemophilia Hemophilia is a rare genetic blood disorder in which blood clotting is impaired. This occurs because specific genes producing clotting factors VIII or IX are dysfunctional. As it is an inherited condition, signs often show up in early childhood. The main sign is excessive bleeding, occurring both externally from cuts and internally into joints or organs. Other signs include nose bleeding, easy bruising, and bleeding during or after surgery. Treatment includes administering…

Shingles, also known as herpes zoster, is a viral infection caused by the reactivation of the varicella-zoster virus, which is the same virus that causes chickenpox. The reactivation after dormancy in adulthood causes extremely painful rash which is avoidable by awareness and vaccination. Here are a few things everyone must know about Shingles. What is Shingles? Shingles is a viral disease caused by the same virus that causes chickenpox, also known as the Herpes Zoster virus. The virus remains…

Diabetic Macular Edema or DME is a growing concern in India especially because it is most prevalent in persons with Diabetes. Learn more about the causes, symptoms and treatment options available for DME. Dr. Padmaja Kumari Rani, Network Head, Tele-ophthalmology and vitreoretinal surgeon at L V Prasad Eye Institute provides valuable information on treatment and prevention of DME.    What is Diabetic Macular Edema? Diabetic Macular Edema (DME) is a condition that affects the retina,…

The thyroid gland plays a crucial role in controlling vital functions. There are multiple thyroid disorders. PatientsEngage addresses some of common and frequently asked questions on thyroid related issues. The thyroid gland is one of the most essential glands in the body. It is fundamental to the functioning of several organs, such as the kidneys, liver, brain, heart, and even skin. The thyroid is a butterfly-shaped gland at the lower-front part of the neck, just below the Adam's apple. It is…