Does the current pharmacological agents adequately address the two hall marks of type 2 diabetes- progressive insulin deficiency and insulin resistance?. Is there a need for inclusion of non-alcoholic fatty liver and relative deficiency of gut microbiota as additional markers for type 2 diabetes? Is there an immediate need for inclusion of intensive essential nutrients known to increase insulin sensitivity, reverse the fatty liver and probiotics in the treatment guidelines irrespective of the choice of the pharmacological agents?
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