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Submitted by Aparna on 22 January 2015

Despite known risks for older people, use of benzodiazepines—a class of sedative and anti-anxiety medications—remains common in this group. The findings raise questions about why so many prescriptions are written for older adults when there are often safer alternatives.

 

Benzodiazepines include the medications alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan). These drugs are widely prescribed to treat anxiety and sleep problems. But while effective, they have serious risks—especially when used over long periods. Long-term use can lead to dependence and withdrawal symptoms when discontinued. Benzodiazepines can impair cognition, mobility, and driving skills in older people, as well as increase the risk of falls. A recent study also found an association between benzodiazepine use in older people and increased risk of Alzheimer’s disease.

Practice guidelines now recommend psychotherapy approaches and antidepressants as the initial treatment for anxiety. For insomnia, guidelines recommend behavioral interventions as first treatment.

http://www.nih.gov/researchmatters/january2015/01122015benzodiazepine.htm