Parkinson's Disease - The Shaking Palsy

The loss of production of the chemical dopamine due to nerve degeneration in the brain (esp. the substania nigra) is the key component for the inception of this movement disorder. Dopamine is the messenger that is responsible for coordinating movement, balance and the reward system with other nerve and muscle cells.  As of now, we do not know the exact cause of the loss of nerve cells that leads to Parkinson’s disease. Researchers believe it may be due to genetic or environmental factors,…

Symptoms vary from person to person. Which symptom will affect you, in which order and how your symptoms may progress are difficult to predict. Parkinson symptoms are often categorised as Motor and Non-motor. Motor symptoms are essentially due to akinesia (poverty of action, difficulty initiating movements,) and bradykinesia (slow movements).  The following are some of the symptoms and signs seen: Tremor in Parkinson’s can be of 2 types, either a resting tremor or an action tremor.…

Dopamine is a Brain Chemical that helps to control muscle movement. In Parkinson's Disease the brain cells that make dopamine slowly die. The resultant lack of dopamine in body leads to physical symptoms such as slowness of movement, unusual stiffness in body, tremors and loss of balance. Depression, anxiety, constipation, speech-swallowing problems are some of the many other affections of Parkinson's Disease.          

Dr. Pettarusp Wadia, Consultant Neurologist and Movement Disorder Specialist, Jaslok Hospital and Research Centre, Mumbai, speaks to Dr Shital Raval about the latest treatments to manage Parkinson’s Disease.  Is Parkinson's a genetic condition? In about 5% of the adult population and 25% of the young-onset Parkinson's disease population, a single gene can be identified. However research is on to identify if certain genes make a person more susceptible to develop…

Mrs Balasubramaniam has been looking after her husband, 83, who has Parkinson’s Disease, for more than a decade. She shares symptoms, treatments and caregiving tips.   When was your husband diagnosed with Parkinson’s Disease? My husband was diagnosed with Parkinson’s Disease about 10 to 12 years back, but he probably had symptoms much before that were not very noticeable, such as mild abnormality of gait or sticking out his tongue occasionally. What were the early…

Parkinson’s disease is a progressive neurodegenerative disorder caused by deterioration of nerve cells (neurons) in the part of the brain called the substantia nigra. The death or damage to the nerves and the central nervous system causes deficiency of one of the important chemical neurotransmitter or messengers called dopamine. The lack of or decrease in the dopamine levels hinders the brain from sending signals to other cells within the brain and muscles. Movements tend to slow down or…